Sponsored by the Lasker Foundation

*CME Accredited

Dr. Nabel will be interviewed by Alex Waldman, DPhil, APSA President

*CME Accredited

Chair(s): Zheng hong Tan & Kayla Schwartz, APSA Events Co-Chairs 

Chairs: John Ioannidis, MD, DSc, Benjamin Humphreys, MD, PhD, Alex Waldman, DPhil

• 11:00 - 11:04 AM - Patrick A. DeSouza, Washington University School of Medicine
  • An aberrant INSM1-dependent intermediate neuronal progenitor state drives tumorigenesis in a human stem cell model of glioblastoma
     
• 11:04 - 11:08 AM - Jawad Fares, Feinberg School of Medicine, Northwestern University 
  • High throughput screening identifies metixene as an NDRG1-mediated incomplete autophagy inducer in metastatic brain cancer
     
• 11:08-11:12 AM - Holly H. Guo, University of Texas Southwestern Medical Center
  • Dibenzothiazepinones are inhibitors of NVL that cause p53-dependent apoptosis by blocking 60S ribosome assembly
     
• 11:12-11:16 AM - Hannah M. Lynn, Washington University School of Medicine
  • A carbohydrate-focused approach to developing microbiome directed therapeutic foods for undernutrition
     
• 11:16-11:20 AM - Abraham T. Ogbaslase, Washington University School of Medicine
  • The role of B cell and microglial BTK signaling in the pathogenesis of experimental autoimmune encephalomyelitis
     
• 11:20-11:24 AM - Preethi K. Periyakoil, Memorial Sloan Kettering Cancer Center
  • Effective and Scalable Deconvolution of Spatial Transcriptomics Data with Dirichlet Variational Autoencoders
     
• 11:24-11:28 AM - Clara D. Si, Vanderbilt University Medical Center
  • Receptor Activator of NF-κB Ligand signaling dampens monocyte innate immune responses against intracellular bacteria
     
• 11:28-11:32 AM - Max M. Wang, Northwestern University
  • Targeted degradation of undruggable proteins using a novel heterobifunctional proteomimetic platform

*By invitation ONLY

*CME Accredited

Moderators: Anna Greka, Dianna Milewicz and Cynthia Tang

• 1:00 PM - 1:20 PM
  • Michael . Snyder, PhD: Disrupting Healthcare Using Deep Data and Remote Monitoring
• 1:20 PM - 1:40 PM
  • Navdeep Chandel, PhD: Mitochondria Signaling Control of Physiology and Disease
• 1:40 PM - 2:05 PM
  • AAP Helen M. Ranney Award, MD Award: Lucila Ohno-Machado, MD, PhD, Medical AI for All
• 2:05 PM - 2:20 PM
  • ASCI New Member: Read Pukkila-Worley, MD: Bacterial Patterns of Pathogenesis in Intestinal Immunity
• 2:20 PM - 2:35 PM
  • AAP New Member: Michael Ward, MD, PhD: Uncovering the Hidden Biology of Lysosomes in Neurons and Disease
• 2:35 PM - 2:50 PM
  • ASCI New Member: Tamia A. Harris-Tryon, MD, PhD: Dissecting Host-Microbial Interactions at the Skin Surface
• 2:50 PM - 3:05 PM
  • ASCI's 2024 Awardee Recognition (Ropes, Sullivan, Seldin-Smith)
    • Louis W. Sullivan, MD, Award: Deidra C. Crews, MD, ScM
    • Marian W. Ropes, MD, Award: Renee Yuen-Jan Hsia, MD, MSc
    • Seldin~Smith Award: Benjamin Izar, MD, PhD

*CME Accredited

Moderators: Michael Diamond, Marzieh Ghiasi and Priscilla Hsue

• 3:35 PM - 3:55 PM
  • Alison Morris, MD, MS: The Lung Microbiome: From Fiction to Fact
• 3:55 PM - 4:20 PM
  • The 2024 ASCI/Harrington Prize Lecture: Arlene H. Sharpe, MD, PhD
• 4:20 PM - 4:40 PM
  • ASCI Presidential Address: Benjamin D. Humphreys, MD, PhD
• 4:40 PM - 4:55 PM
  • The ASCI's Seldin~Smith Award Lecture:
    Steven E. Mansoor, MD, PhD, 2023 Seldin~Smith Award Recipient
• 4:55 PM - 5:10 PM
  • The ASCI's Ropes Award Lecture:
    Wendy Sarah Garrett, MD, PhD, 2023 Marian W. Ropes, MD, Award Recipient
• 5:10 PM - 5:25 PM
  • The ASCI's Sullivan Award Lecture:
    Duane A. Mitchell, MD, PhD, 2023 Louis W. Sullivan, MD, Award Recipient
• 5:25 PM - 5:50 PM
  • The ASCI’s 2024 Korsmeyer Award Lecture:
    Howard Y. Chang, MD, PhD

Open to All Attendees

*By Invitation Only

Dinner Speaker: Jeffrey Flier, MD: Free Speech and Academic Freedom in Higher Education and Medicine: Challenges and Solutions

*RSVP Required

*Ticketed Event

Dinner Speaker: Wendy Laurel Freedman, FRS: Using the James Webb Space Telescope to measure the scale size and age of the universe

Breakfast will be available in both locations

*CME Accredited

Moderators: Heidi Kong, John Ioannidis, and Alex Waldman 

• 8:00 AM - 8:20 AM
  • Kirsten Bibbins-Domingo, PhD, MD, MAS: Medical Publication During a Dynamic Time: Viewpoint From JAMA and the JAMA Network 
• 8:20 AM - 8:40 AM
  • Rita F. Redberg, MD, MS: Less Is More and Its Role in the Biomedical Sciences and Health Care
• 8:40 AM - 9:00 AM
  • Mitchell A. Lazar, MD, PhD: Clocks Regulating Metabolism: Does Anybody Really Know What Time It Is?
• 9:00 AM - 9:10 AM
  • APSA Trainee Oral Abstract Presentation: Tanner C. Martinez: CUX1 Levels Control Hematopoietic Stem Cell Fate and Plasticity
• 9:10 AM - 9:20 AM
  • APSA RFJF Oral Abstract Presentation: Kenny Kwok-Hei Yu: Transcription Factor FOSL2 Defines a Blood Borne, Functionally Distinct Mesenchymal Glioma Associated Macrophage Program associated with Malignant Glioma Progression
• 9:20 AM - 9:50 AM
  • 2024 APSA~Lasker Foundation Lecture: David Huang, MD, PhD

*CME Accredited

 Moderators: Heidi Kong, John Ioannidis, and Alex Waldman

• 10:15 AM - 10:30 AM
  • Introduced By: John I. Gallin, MD
    2023 Foundation for the National Institutes of Health Trailblazer Prize Lecture: Vinod Balachandran, MD: Personalized RNA Vaccines for Pancreatic Cancer
• 10:30 AM - 11:00 AM
  • Kober Lecture: David Ginsburg, MD, Genetics of Hemostasis: From Bedside to Bench and Back Again

Poster tear down begins at 1:30 PM

*By invitation ONLY

Poster tear down begins at 1:30 PM

*CME Accredited

Moderators: Carey Jansen, Goutham Narla, and Paul Noble

• 1:30 PM - 1:50 PM
  • Stephan Targan, MD: From Bedside to Bench and Back to Bedside: The Road to Precision Medicine in IBD
• 1:50 PM - 2:10 PM
  • Zhijian James Chen, PhD: The Enemy Within - How Does the Immune System Sense DNA as a Danger Signal?
• 2:10 PM - 2:30 PM
  • Akiko Iwasaki, PhD: Immunology of Long COVID
• 2:30 PM - 2:50 PM
  • Ruslan Medzhitov, PhD: Homeostasis, Inflammation, and Disease
• 2:50 PM - 3:00 PM
  • Q&A

Travel Awardee Group Photo in Zurich Ballroom

*CME Accredited

Moderators: Judith James, Zheng Hong Tan, and Vijay Sankaran

• 3:30 PM - 3:50 PM
  • Wendy K. Chung, MD, PhD: Advances in Genomic Medicine: From N of 1 to Population Health
• 3:50 PM - 4:10 PM
  • Carlos D. Bustamante, PhD: Enabling Precision Health At Scale For All
• 4:10 PM - 4:30 PM
  • AAP Presidential Address: John P.A. Ioannidis, MD, DSc: Transparency, Bias, and Reproducibility Across Science: A Meta-Research View
• 4:30 PM - 5:00 PM
  • Kober Medal Presentation
    • Recipient: Daniel L. Kastner, MD, PhD
    • Presenter: John O’Shea, MD

Chair: Cynthia Tang, PhD, APSA President-Elect

Chair: Micaila Curtis

Featuring poster presentations from ASCI’s early-career awardees

*Ticketed Event

Dinner Speaker: Eric Topol, MD: AI’s Transformation of Medicine

*Ticketed Event

Open to All Attendees

*Additional Registration Required For this Event.  

Click Here for More Information and to Register.

Event Geared for APSA Attendees

*Ticketed Event 

Chair: Luke Cooksey

Session Geared for APSA Attendees

Chairs:

• Deborah Rupert
• Anne Wells

Chair: Brea Lombardo, MD

Session Geared for APSA Attendees

Chair: Rincon Jagarlamudi

This Residency Luncheon facilitates interaction between future residency applicants and residency programs. It’s a great opportunity for young physician scientists to learn more about residency programs available throughout the US.          

Chairs:

• Zheng Hong Tan, PhD
• Kayla Schwartz