CME Accredited

Sponsored by the Albert and Mary Lasker Foundation

Moderator: Eli Wisdom, APSA Vice President

Peggy Hamburg, MD
InterAcademy Partnership (IAP)

CME Accredited

Moderator: Kayla Schwartz, APSA Events Co-Chair

Vivian S. Lee, MD, PhD, MBA
Harvard Business School

CME Accredited

~4 min talks picked from abstract submissions

Moderators: Cynthia Tang, Paul Noble, Anna Greka

11:00-11:04 AM: Graham Hogg, Washington University School of Medicine MSTP
Combined Flt3L and CD40 agonism restores dendritic cell driven T cell immunity in mouse models and patients with pancreatic cancer

11:04-11:08 AM: Najwa Labban, University of Virginia
Patient-derived response estimates from zero-passage organoids of luminal breast cancer

11:08-11:12 AM: Seungyeon Lee, Johns Hopkins
A Novel Mediator of Cardiac Hypertrophy and Heart Failure - Modulation of YAP via O-GlcNAcylation in the Heart

11:12-11:16 AM: Isabella L Melena, Washington University in St. Louis
Primary cilia regulate GLP-1 signaling in pancreatic beta cells.

11:16-11:20 AM: Sakila Nazia, Tri-Institutional MD-PhD Program
Arginine biosynthesis: a carbamoyl phosphate salvage pathway in Mycobacteria tuberculosis (Mtb)

11:20-11:24 AM: Ezekiel Olumuyide, Icahn School of Medicine
HLA II genetics influence lung cancer Immunosurveillance

11:24-11:28 AM: Pablo Sanchez Vela, Memorial Sloan Kettering Cancer Center
Clonal hematopoiesis is an actionable driver of treatment resistance and metastasis in patients with solid tumors

11:28-11:32 AM: Alec Stepanian, Tufts Medical Center
BCR-Abl inhibitor ponatinib, but not the new drug asciminib, induces thromboinflammation, atherosclerotic inflammation, and plaque rupture in mice

11:32-11:36 AM: Zachary H Walsh, Columbia University 
Massively scalable generation, discovery, and clinical (re-)classification of inborn errors of immunity using cutting-edge genome engineering

11:36-11:40 AM: Tiankai Yin, Washington University in St. Louis 
VISTA as a Mediator of Immune Suppression in AML Initiated by DNMT3A and NPM1 Mutations

CME Accredited 
Purpose, Persistence, and Progress: Building the Next Generation of Physician-Scientists

Cynthia Tang, PhD
University of North Carolina School of Medicine​​​​​

CME Accredited

Moderators: Paul Noble, Kayla Schwartz, Julie Bastarache

1:00 PM - 1:20 PM: 
Selective autophagy: supporting healthy aging one protein at a time
Ana Maria Cuervo, MD, PhD 
Albert Einstein College of Medicine

1:20 PM - 1:40 PM: 
Sex, Cancer and the Y Chromosome
Dan Theodorescu, MD PhD
University of Arizona Cancer Center

1:40 PM - 1:50 PM
APSA Trainee Oral Abstract Presentation
Ectopic NMDAR expression unmasks germline-encoded autoimmunity
Sam O. Kleeman



1:50 PM - 2:05 PM
ASCI New Member
The Hidden Cost of Immunity: APOL1 and the Channelopathy of Kidney Disease
Opeyemi A. Olabisi, MD, PhD
Duke University School of Medicine

2:05PM - 2:20PM
AAP New Member
Advancing Precision Prevention via the Social Exposome: The Area Deprivation Index (ADI)
Amy Kind, MD, PhD
University of Wisconsin School of Medicine and Public Health


 

2:20PM - 2:35PM
ASCI New Member
Loss of Tissue Resident NK Cells Associates With Pregnancy Complications in Uterus Transplant Recipients
Paige M. Porrett, MD, PhD
University of Alabama at Birmingham

2:35PM - 2:55PM
AAP Ranney Award
Closing the loop in hemoglobin disorders
Swee Lay Thein, MB, BS, DSc
National Institutes of Health

CME Accredited

Moderators: Priscilla Hsue, Cynthia Tang, Eli Wisdom, Susan Quaggin, Elizabeth Speliotes 

3:30PM - 3:50PM
Metabolic Perturbations in Human Cancer Progression
Ralph DeBerardinis, MD, PhD
University of Texas Southwestern Medical Center

3:50 PM - 4:10 PM
The ASCI / Harrington Prize Lecture
Cancer Therapy: Target, Modality and Timing
Owen N. Witte, MD
University of California, Los Angeles, David Geffen School of Medicine

4:10 PM - 4:30 PM
ASCI Presidential Address
The Enduring Flame: Our Legacy of Resilience, a Time of Unprecedented Potential, and Igniting the Future of Discovery
Anna Greka, MD, PhD
Broad Institute, Harvard Medical School, and Mass General Brigham

4:30 PM - 4:45 PM 
The ASCI / Seldin~Smith Award Lecture
Tumor-immune interplay during metastatic reactivation from dormancy
Benjamin Izar, MD, PhD
Columbia University Vagelos College of Physicians and Surgeons

4:45 PM - 5:00 PM
The ASCI / Ropes Award Lecture
Dispatch to Discharge: Addressing Systemic Dysfunction in the U.S. Healthcare System
Renee Yuen-Jan Hsia, MD, MSc
University of California, San Francisco, School of Medicine

5:00 PM - 5:15 PM
The ASCI / Sullivan Award Lecture
Centering the Margins to Advance Kidney Health
Deidra C. Crews, MD, FASN
Johns Hopkins University School of Medicine

5:15 PM - 5:35 PM
The ASCI / Korsmeyer Award Lecture
The Enduring Impact of Mentorship in an Era of Scientific Disruption
Kimryn Rathmell, MD, PhD

CME Accredited

Larry S. Schlesinger, MD
Texas Biomedical Research Institute

Julie Louise Gerberding, MD, MPH
Foundation for the National Institutes of Health

**By Invitation Only

Event Location: SPIN Chicago

Address: 344 N. State St., Chicago, IL 60654

Ticketed Event | Non-CME

Non-CME

Dinner Speaker
Evolution in the Age of Us: Understanding the biological impacts of our human footprint
Shane Campbell-Staton, PhD
Princeton University

Breakfast will be offered near plenary session room and within the poster hall.

CME Accredited

Moderator: Anna Greka 

8:00 AM - 9:00 AM
Fireside Chat 1 Panel: The Physician-Scientist Pipeline -- Challenges and Opportunities

David Altshuler, MD, PhD
Vertex Pharmaceuticals





 

Irit Ben-Aharon, MD, PhD
Rambam Health Care Center

Nancy Brown, MD
Yale University

Jonathan Epstein, MD
Perelman School of Medicine, University of Pennsylvania

Kimryn Rathmell, MD, PhD

9:00 - 9:30 AM
Break

Moderators: Juanita Merchant, Rohini Guin, Julie Gerberding

9:30 AM - 9:50 AM
The ASCI / Scharschmidt~Crawford Distinguished Lectureship
Humanizing Drug Discovery
David Altshuler, MD, PhD
Vertex Pharmaceuticals

9:50 AM - 10:00 AM
APSA RFJF Oral Abstract Presentation
Neuronally differentiated endothelial cell subtype regulates organ blood flow and immune balance
Georgina Gyarmati



10:00 AM - 10:30 AM
APSA~Lasker Laureate Lecture
Chemistry Matters: From a Putative Peptide to Effective Medicines for Diabetes and Obesity
Sponsored by the Albert and Mary Lasker Foundation
Svetlana Mojsov, PhD
Rockefeller University

10:30AM - 10:45AM
FNIH Trailblazer Prize Lecture (2024 recipient)
What Patients Can Teach Us About Blood Cell Production
Vijay G. Sankaran, MD, PhD
Harvard Medical, Boston Children's Hospital, Dana-Farber/ Boston Children’s Cancer and Blood Disorders Center

*Poster teardown directly after

CME Accredited

Moderator: Paul Noble

1:30 PM - 1:50 PM
Building a better biotech – the story of Regeneron
George D. Yancopoulos, MD, PhD
Regeneron Pharmaceuticals

1:50 PM - 3:00 PM
Fireside Chat 2 Panel: The Future of Biomedicine
Victor Dzau, MD
Duke University







Julie Louise Gerberding, MD, MPH
Foundation for the National Institutes of Health







John P.A. Ioannidis, MD, DSc
Stanford University

George D. Yancopoulos, MD, PhD
Regeneron Pharmaceuticals

CME Accredited

Moderators: Priscilla Hsue, Isabelle Kwan, Zolt Arany, Paul Noble

3:30 PM - 3:50 PM
Physician Scientist: Academia & Pharmaceutical Industry
Aida Habtezion, MD, MSc, FRCPC, AGAF
Stanford University









3:50 PM - 4:10 PM
Pursuing the Pathogenesis of Cystic Fibrosis
Mike Welsh, MD
University of Iowa

4:10 PM - 4:30 PM
AAP Presidential Address
The Unbridled Joy of the Clinician Scientist and the Community of the AAP
Paul Noble, MD
Cedars Sinai Medical Center

4:30 PM - 5:00 PM
Kober Medal Presentation (Recipient: Mitch Lazar, Presenter: Myles Brown)

Mitchell Lazar, MD, PhD
University of Pennsylvania Perelman School of Medicine

Myles Brown, MD
Dana-Farber Cancer Institute and Harvard Medical School






 

5:00 PM
AAP Business Meeting

CME Accredited

Moderators: Jessica Weng and Sahra Gabure, APSA Justice, Equity, Diversity, and Inclusion Co-Chairs, and Karen Osei-Boamah, Student National Medical Association

Pringl Miller, MD
Physician Just Equity

CME Accredited

Moderator: Jessica Ding, APSA Policy Chair

Susan Cheng, MD, MMSc, MPH
Smidt Heart Institute at Cedars-Sinai









Elbert Huang, MD, MPH, FACP
University of Chicago

Ticketed Event | Non-CME

The Food & Science Evening celebrates the intersection of fine cuisine and science. It is an evening of revelry, impeccable culinary creations, and excellent poster presentations from ASCI Early-Career Awardees.

Ticketed Event | Non-CME

Dinner Speaker:
How to Die Young at a Very Old Age
Nir Barzilai, MD
President of the Academy for Health & Lifespan Research
Albert Einstein College of Medicine

Ticketed Event | Non-CME

Dinner Speaker:
Beatrice Renault, PhD
Albert and Mary Lasker Foundation

Non-CME

The workshop gathers faculty, staff engaged in training physician-scientists at the pre- and post-graduate level, and trainees to share best practices, network, and explore the theme: The Future of Physician-Scientist Training: Adapting to a Changing Landscape with Inclusive Excellence.

Click here for more information and to secure your registration.
*A separate registration is required to attend this workshop.

Sponsored in part by the American Association of Immunologists

Click here to access the list of participating programs.

For any attendees that will need to store their luggage throughout the day on Sunday, we have a dedicated luggage storage located in the Zurich Foyer.

Non-CME

Moderators: Marzieh Ghiasi, Resident and Fellow Member-At-Large Chair 

Dineo Khabele, MD
Washington University School of Medicine in St. Louis

Ebru Erbay, MD, PhD
University of California, Los Angeles 

Non-CME

Moderator: Zoe Boudart, APSA Social Sciences and Humanities

Ashish Premkumar, MD, PhD
The University of Chicago Pritzker School of Medicine

Click here to access the list of participating programs.
**Check back for more!