Myles Brown is the Emil Frei III Professor of Medicine at Dana-Farber Cancer Institute and Harvard Medical School. He received his undergraduate degree from Yale University and his medical degree from Johns Hopkins University. He then completed residency in internal medicine at Brigham and Women's Hospital, and a fellowship in hematology/oncology at DFCI. Prior to starting his own laboratory, he was a research fellow in the labs of David Livingston and Phillip Sharp.

From 2002-2010 he served as Chief of the Division of Molecular and Cellular Oncology at the Dana-Farber. In 2010 together with Shirley Liu he founded the Center for Functional Cancer Epigenetics at the Dana-Farber.

Dr. Brown's research laboratory focuses on elucidating the epigenetic factors underlying the action of steroid hormones. This work has important implications both for normal physiology and for the treatment of hormone-dependent malignancies including breast and prostate cancer. He is recognized for three seminal discoveries. His lab helped open the steroid receptor co-regulator field, illuminated the dynamic nature of receptor and coregulator interactions with the genome and elucidated the importance of epigenetically determined distant cis-regulatory steroid receptor binding sites. His contributions have uniquely reformulated the understanding of steroid hormone action in normal physiology and in hormone-dependent cancer.