A physician-scientist, Dean Jain is internationally recognized for studies that established a central role for Kruppel-like factors, a family of DNA transcription factors, in cardiovascular biology, innate immunity, and metabolism. In his previous roles, he oversaw basic and clinical research in one of the nation’s largest graduate medical education programs, with over 1,100 residents and fellows.

Nationally, Jain’s clinical and academic contributions have been recognized through numerous honors including election to the National Academy of Medicine, the American Society for Clinical Investigation, the Association of American Physicians, and the Association of University Cardiologists. In 2017, Jain and five colleagues (including two Nobel laureates) founded the Physician-Scientist Support Foundation, a nonprofit that strives to build a sustainable and diverse physician-scientist workforce through financial and research support for fundamental discoveries that improve human health.

Dean Jain obtained his undergraduate degree Summa cum laude from the University of Buffalo as well as his MD from the University of Buffalo School of Medicine. He completed residency in internal medicine in Boston, and fellowships at Harvard School of Public Health and Brigham and Women’s Hospital. He subsequently joined the Cardiovascular Division at Brigham and Women’s and was an assistant professor at Harvard Medical School until moving to Case Western Reserve and University Hospitals in 2006.