CME Accredited

~4 min talks picked from abstract submissions

Moderators: Cynthia Tang, Paul Noble, Anna Greka

11:00-11:04 AM: Graham Hogg, Washington University School of Medicine MSTP
Combined Flt3L and CD40 agonism restores dendritic cell driven T cell immunity in mouse models and patients with pancreatic cancer

11:04-11:08 AM: Najwa Labban, University of Virginia
Patient-derived response estimates from zero-passage organoids of luminal breast cancer

11:08-11:12 AM: Seungyeon Lee, Johns Hopkins
A Novel Mediator of Cardiac Hypertrophy and Heart Failure - Modulation of YAP via O-GlcNAcylation in the Heart

11:12-11:16 AM: Isabella L Melena, Washington University in St. Louis
Primary cilia regulate GLP-1 signaling in pancreatic beta cells.

11:16-11:20 AM: Sakila Nazia, Tri-Institutional MD-PhD Program
Arginine biosynthesis: a carbamoyl phosphate salvage pathway in Mycobacteria tuberculosis (Mtb)

11:20-11:24 AM: Ezekiel Olumuyide, Icahn School of Medicine
HLA II genetics influence lung cancer Immunosurveillance

11:24-11:28 AM: Pablo Sanchez Vela, Memorial Sloan Kettering Cancer Center
Clonal hematopoiesis is an actionable driver of treatment resistance and metastasis in patients with solid tumors

11:28-11:32 AM: Alec Stepanian, Tufts Medical Center
BCR-Abl inhibitor ponatinib, but not the new drug asciminib, induces thromboinflammation, atherosclerotic inflammation, and plaque rupture in mice

11:32-11:36 AM: Zachary H Walsh, Columbia University 
Massively scalable generation, discovery, and clinical (re-)classification of inborn errors of immunity using cutting-edge genome engineering

11:36-11:40 AM: Tiankai Yin, Washington University in St. Louis 
VISTA as a Mediator of Immune Suppression in AML Initiated by DNMT3A and NPM1 Mutations