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Program

Friday, April 26
8:30 a.m. – 12:30 p.m. APSA Business Meeting
1:00 p.m. – 3:00 p.m. Poster Setup
12:30 p.m. – 3:30 p.m. APSA Plenary Session
12:30 p.m. –
1:00 p.m.
APSA Keynote
Public Scholarship and the Role of Scientists
Debra Houry, MD, MPH
Emory University School of Medicine
1:00 p.m. –
1:30 p.m.
APSA Keynote
Jonathan Epstein, MD

Perelman School of Medicine at the University of Pennsylvania
2:00 p.m. –
3:00 p.m.
APSA Session I: Women in Medicine Panel
3:00 p.m. –
3:30 p.m.
APSA Keynote
The Cancer Genome in Biology and Therapy
Levi A. Garraway, MD, PhD
Harvard Medical School, Dana-Farber Cancer Institute
3:30 p.m. – 6:00 p.m. Plenary Session I – Understanding Disease Mechanisms to Improve Human Health
3:30 p.m. –
4:00 p.m.
Scaling up the potential of clinical research
Francis Collins, MD, PhD
National Institutes of Health
4:00 p.m. –
4:30 p.m.
Hepatitis C: Is the end in sight?
Charles Rice, PhD
Rockefeller University
4:30 p.m. –
4:45 p.m.
Career Development Awardee Presentation
4:45 p.m. –
5:15 p.m.
Mitochondrial protein acylation and metabolic regulation
Eric Verdin, MD
Gladstone Institutes, University of California, San Francisco
5:15 p.m. –
5:45 p.m.
Induction of pluripotency by defined factors
Shinya Yamanaka, MD, PhD
2012 Nobel Prize in Physiology or Medicine

Center for iPS Cell Research and Application (CiRA), Japan, and Gladstone Institutes (UCSF)
5:45 p.m. –
6:00 p.m.
Q&A
6:00 p.m. – 7:00 p.m. ASCI President's Reception
(by invitation only)
6:00 p.m. – 9:30 p.m. Poster Viewing
7:00 p.m. – 9:00 p.m. AAP President's Dinner
(by invitation only)
Mid-America Club
7:00 p.m. – 9:00 p.m. ASCI Dinner and New Member Induction Ceremony
(ticketed guests only)
Clinical Research: The Uphill Climb
Speaker: David G. Nathan, MD
Harvard Medical School, Dana-Farber Cancer Institute
7:00 p.m. – 9:00 p.m. APSA Dinner Outing: Interest Groups
(On Your Own) Groups will meet by the Registration Desk at the Fairmont Hotel
9:00 p.m. – Midnight APSA Welcome Reception
APSA Presidential Address
Speaker: Dania Daye, MD, PhD Candidate, HHMI-NIBIB Interfaces Scholar, University of Pennsylvania School of Medicine
Saturday, April 27
7:00 a.m. – 8:15 a.m. Mentoring Breakfast
8:15 a.m. – 11:15 a.m. Plenary Session II – Understanding Disease Mechanisms to Improve Human Health
8:15 a.m. –
8:45 a.m.
Reflections of a former MSTP director on physician/scientist training
Kevin Shannon, MD
University of California, San Francisco
8:45 a.m. –
9:15 a.m.
Developing new prostate cancer drugs
Charles Sawyers, MD
Memorial Sloan-Kettering Cancer Center
9:15 a.m. –
9:30 a.m.
APSA Trainee Presentation
Role of FRS2 and FGF/FGFR autocrine signaling in the proliferation of ovarian cancer cells
Leo Y. Luo, BS
Broad Institute of Harvard and MIT
9:30 a.m. –
10:00 a.m.
Direct cardiac reprogramming: From developmental biology to regeneration
Deepak Srivastava, MD
Gladstone Institutes, University of California, San Francisco
10:00 a.m. – 10:30 a.m. Break
10:30 a.m. –
11:00 a.m.
Novel mechanisms by which adipose tissue regulates systemic insulin sensitivity and the risk for diabetes
Barbara Kahn, MD
Harvard Medical School, Beth Israel Deaconess Medical Center
11:00 a.m. –
11:15 a.m.
APSA Trainee Presentation
Heat shock Protein 70 demonstrates IL-10 mediated immune modulation in experimental colitis
InYoung Kim, PhD
University of Chicago
11:15 a.m. –
11:45 a.m.
Unifying role for prions in degenerative diseases
Stanley Prusiner, MD
1997 Nobel Prize in Physiology or Medicine
University of California, San Francisco
11:45 a.m. – 1:30 p.m. Poster Session with Lunch
1:30 p.m. – 2:00 p.m. Poster Dismantle
1:30 p.m. – 2:15 p.m. APSA Breakout Sessions:
Residency 101
Writing for Basic Science & Clinical Journals
1:30 p.m. – 4:10 p.m. ASCI and AAP New Member Presentations
1:30 p.m. –
1:50 p.m.
Telomerase and idiopathic pulmonary fibrosis
Mary Armanios, MD
(New ASCI Member)
Johns Hopkins University School of Medicine
1:50 p.m. –
2:10 p.m.
VEGF and the glomerular barrier - two sides to the story
Susan Quaggin, MD
(New AAP Member)
Northwestern University
2:10 p.m. –
2:30 p.m.
Regulation of the dendritic cell and macrophage lineage
Miriam Merad, MD, PhD (New ASCI Member)
Mount Sinai School of Medicine
2:30 p.m. –
2:50 p.m.
Treating the untreatable: An exome sequencing approach in neurodevelopmental disease
Joseph Gleeson, MD (New AAP Member)
University of California, San Diego
3:00 p.m. –
3:30 p.m.
Break
3:30 p.m. –
3:50 p.m.
Mapping the origins of cancer
Richard James Gilbertson, MD, PhD (New ASCI Member)
St. Jude Children's Research Hospital
3:50 p.m. –
4:10 p.m.
The search for disease genes: What Mendel can tell us about medicine
David Valle, MD (New AAP Member)
Johns Hopkins University School of Medicine
2:30 p.m. – 3:15 p.m. APSA Session – Policy Panel
Moderator: Barry Coller, MD
Rockefeller University
Panelists:
Mike Bristow, MD, PhD
University of Colorado
Anada Chakrabarty, PhD
University of Illinois, Chicago
Francis Collins, MD, PhD
Director, National Institutes of Health
3:00 p.m. – 3:30 p.m. Break
4:10 p.m. – 4:45 p.m. APSA Keynote
Epstein-Barr virus and human cancer: The good, the bad and the ugly
Shannon Kenney, MD
University of Wisconsin-Madison School of Medicine and Public Health
4:45 p.m. – 5:00 p.m. APSA Trainee Presentation
T-bet dictates CD8+ T cell tolerance versus immunity following antigen recognition
Stephanie R. Jackson, BSE, MS
Saint Louis University School of Medicine
5:00 p.m. – 5:30 p.m. AAP Presidential Address:
Seeking sustainable solutions to global health challenges: No more Band-Aids
Warner Greene, MD, PhD
Gladstone Institutes, University of California, San Francisco
5:30 p.m. – 6:00 p.m. ASCI Presidential Address:
The perfect storm: Challenges and opportunities for translational research
William C. Hahn, MD, PhD
Harvard Medical School, Dana-Farber Cancer Institute
7:30 p.m. – 9:00 p.m. APSA Dinner
Speaker: Matthew Lewin, MD, PhD
Center for Exploration and Travel Health, California Academy of Sciences
7:00 p.m. – 10:00 p.m. AAP Annual Reception and Dinner
A Funny Thing Happened on the Way to Stockholm
Robert Lefkowitz, MD
2012 Nobel Prize in Chemistry
Duke University
10:00 p.m. – Midnight Dessert Reception (open to all attendees)

Sunday, April 28
7:00 a.m. – 8:15 a.m. Mentoring Breakfast
8:00 a.m. – 8:20 a.m. AAP Business Meeting
8:20 a.m. – Noon Plenary Session III – Understanding Disease Mechanisms to Improve Human Health
  8:20 a.m. –
8:30 a.m.
Best Poster Award Presentation
8:30 a.m. –
9:15 a.m.
Kober Medal Presentation
Recipient: John T. Potts, Jr., MD
Massachusetts General Hospital

Presenter: J. Larry Jameson
Perelman School of Medicine, University of Pennsylvania
9:15 a.m. – 10:00 a.m. ASCI/Stanley J. Korsmeyer Award Lecture
Bruce Beutler, MD
2011 Nobel Prize in Physiology or Medicine

UT Southwestern Medical Center
10:00 a.m. – 10:45 a.m. Targeting the gut to treat the heart
Stanley Hazen, MD, PhD
Cleveland Clinic
10:45 a.m. –
11:00 a.m.
APSA Trainee Presentation
Systemic Type I interferons indirectly promote epithelial proliferation and turnover
Lulu Sun, BSc
Washington University in St. Louis School of Medicine
11:00 a.m. –
11:15 a.m.
APSA Trainee Presentation
Decreased puberty and fertility development in NELF KO mice due to impaired GnRH neuron migration
Samuel D. Quaynor, BA
Georgia Health Sciences University
11:15 a.m. –
Noon
APSA Keynote
MRI: From science to society
Vivian S. Lee, MBA, MD, PhD
University of Utah
Noon – 1:00 p.m. APSA Session
Post Graduate Opportunities Panel: Industry, Government, Academia
1:00 p.m. – 2:30 p.m. APSA Residency Luncheon