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Program

Friday, April 25
8:30 a.m. – 11:00 a.m. APSA Business Meeting
11:00 p.m. – 1:00 p.m. APSA Session I
11:00 a.m. – 11:45 a.m. Invited Speaker:
Mark Courtney, MD
Northwestern University
Noon – 12:45 p.m. Invited Speaker:
Brian Kobilka, MD

Stanford University
1:00 p.m. – 3:00 p.m. Poster Setup
1:00 p.m. – 6:00 p.m. Plenary Session I: Understanding Disease Mechanisms to Improve Human Health
1:00 p.m. – 1:30 p.m. Genomics and the future of diagnosis, prevention and therapeutics
Richard P. Lifton, MD, PhD
Yale University
1:30 p.m. – 2:00 p.m. Close to the bone: Novel genes that remodel the skeleton
Laurie H. Glimcher, MD

Weill Cornell Medical College
2:00 p.m. – 3:00 p.m.ASCI and AAP New Member Presentations
2:00 p.m. – 2:15 p.m. AAP New Member Presentation
John A. Stamatoyannopoulos, MD
University of Washington School of Medicine
Decoding the Human Genome
2:15 p.m. – 2:30 p.m.ASCI New Member Presentation
Anthony W. Ferrante, Jr., MD, PhD
Columbia University College of Physicians & Surgeons
Immune Regulation of Adipose Tissue Mass
2:30 p.m. – 2:45 p.m. AAP New Member Presentation
Lisa Cooper, MD
Johns Hopkins University
The Role of Patient-Physician Relationships in Overcoming Health and Healthcare Disparities
2:45 p.m. – 3:00 p.m.ASCI New Member Presentation
Christoph Klein, MD, PhD
University Children’s Hospital, Dr. von Haunersches Kinderhospital
Novel Genetic Defects of the Human Immune System
2:00 p.m. – 3:00 p.m. APSA Panel: The Intertwining Growth of Women and Medicine in the 21st Century
3:00 p.m. – 3:30 p.m.Break
3:30 p.m. – 4:00 p.m.Targeting the PI3K/AKT/mTOR pathway in breast cancer
José Baselga, MD, PhD

Memorial Sloan–Kettering Cancer Center
4:00 p.m. – 4:30 p.m.Engineering T cells for cancer: CARs and beyond
Carl June, MD

University of Pennsylvania School of Medicine
4:30 p.m. – 4:45 p.m.JCI Editor Update
4:45 p.m. – 5:15 p.m.ASCI Presidential Address
Leading by example: pastors, mentors, physician-scientists and the ASCI
Peter Tontonoz, MD PhD
University of California, Los Angeles
5:15 p.m. – 5:45 p.m. ASCI/Stanley J. Korsmeyer Award Lecture
Autophagy: A Cornerstone of Cellular Health
Beth Levine, MD
UT Southwestern Medical Center
5:45 p.m. – 6:15 p.m. Lasker Award Lecture
Therapeutic applications of VEGF inhibitors: progress and challenges
Napoleone Ferrara, MD
University of California, San Diego
6:00 p.m. – 9:30 p.m.Poster Viewing
6:15 p.m. – 7:15 p.m.ASCI Welcome Reception and Poster Viewing
7:00 p.m. – 9:00 p.m.AAP Offsite President's Dinner
7:00 p.m. – 9:00 p.m.APSA Dinner Outing: Interest groups
Groups will meet by the Registration Desk at the Fairmont Hotel
(Local Restaurants)
7:30 p.m. – 9:30 p.m.ASCI Dinner and New Member Induction Ceremony
Speaker: Joseph L. Goldstein, MD
UT Southwestern Medical Center
How to Solve a Scientific Puzzle: Clues from Stockholm and Broadway
9:00 p.m. – Midnight APSA Welcome Reception & Presidential Address
Speaker: Evan Noch, MD, PhD
Weill-Cornell Medical Center
Saturday, April 26
7:00 a.m. – 8:00 a.m.AAP Council Meeting
7:00 a.m. – 8:00 a.m.Mentoring Breakfast
8:00 a.m. – 5:45 p.m.Plenary Session II: Understanding Disease Mechanisms to Improve Human Health
8:15 a.m. – 8:45 a.m. Gene therapy for Leber's Congenital Amaurosis as a stepping stone for treating other blinding diseases
Jean Bennett, MD
University of Pennsylvania School of Medicine
8:45 a.m. – 9:15 a.m. Perturbing the early life microbiome and its consequences
Martin Blaser, MD
New York University School of Medicine
9:15 a.m. – 9:30 a.m.APSA Trainee and Oral Abstract Presentation:
David Y. Chiang
Baylor College of Medicine
Ryanodine-Receptor Mediated Calcium Leak Drives Progression of Atrial Fibrillation
9:30 a.m. – 10:00 a.m.Strategies to fix a broken heart
Christine E. Seidman, MD

Brigham and Women's Hospital, Harvard Medical School
10:00 a.m. – 10:30 a.m.Break
10:30 a.m. – 11:00 a.m. Inaugural ASCI/Harrington Prize Lecture
Found in Translation: New Insights into the Pathogenesis and Treatment of Marfan Syndrome and Related Disorders
Harry Dietz, MD
Johns Hopkins Medicine
11:00 a.m. – 11:15 a.m.APSA trainee oral abstract presentation
11:15 a.m. – 11:45 a.m.APSA Keynote Speaker:
Mary Klotman, MD

Duke University
11:45 a.m. – 1:30 p.m.Poster Session with Lunch
12:45 p.m. – 1:30 p.m.Poster Reviewer Meeting
1:30 p.m. – 2:00 p.m.Poster Dismantle
1:30 p.m. – 2:00 p.m.APSA Keynote Speaker:
Peter Agre, MD

Johns Hopkins University
Opening Doors Worldwide Through Medical Science
2:00 p.m. – 2:30 p.m. Regenerative medicine: New approaches to healthcare
Anthony Atala, MD

Wake Forest Institute for Regenerative Medicine
2:30 p.m. – 3:00 p.m.The Acute Myeloid Leukemia Genome(s)
Timothy Ley, MD

Washington University School of Medicine
2:30 p.m. – 3:30 p.m. APSA Global Health Panel
Panelists: Shannon Galvin, MD; Robert L. Murphy, MD; Olufunmilayo Olopade, MD, FACP
Moderator: Jaimo Ahn, MD, PhD
2:30 p.m. – 3:30 p.m. APSA Public Outreach of the Physician-Scientist
Panelists: Bechara Choucair, MD; Niranjan Karnik, MD, PhD; Claire Pomeroy, MD, MBA
Moderator: Shwayta Kukreti, MD, PhD
3:00 p.m. – 3:30 p.m.Break
3:30 p.m. – 3:40 p.m.Best Poster Awards
3:40 p.m. – 4:00 p.m.AAP Business Meeting
4:00 p.m. – 4:30 p.m.AAP Presidential Address
Disruptive Innovation as a Driver of Science and Medicine
J. Larry Jameson, MD, PhD
University of Pennsylvania School of Medicine
4:30 p.m. – 5:15 p.m.Kober Medal Presentation Recipient: Elizabeth G. Nabel, MD
Brigham and Women's Hospital, Harvard Medical School

Presenter: Eugene Braunwald, MD
Brigham and Women's Hospital, Harvard Medical School
7:30 p.m. – 9:00 p.m.

APSA Dinner Speaker:
The Rotavirus Vaccine: From Bench to Bedside
Paul Offit, MD

Children's Hospital of Philadelphia

7:00 p.m. – 10:00 p.m.AAP Reception and Dinner Speaker:
Ending the HIV/AIDS Pandemic: Science and Policy
Anthony S. Fauci, MD

National Institute of Allergy and Infectious Disease
10:00 p.m. – Midnight Dessert Reception (open to all attendees)
Sunday, April 27
9:00 a.m. – 10:00 a.m. ASCI/AAP Joint Council Meeting Wrap-Up
8:00 a.m. – Noon APSA Program
8:00 a.m. – 9:30 a.m. Interest Groups & Mentorship
9:30 a.m. – 10:00 a.m. APSA Keynote Speaker:
Hedvig Hricak, MD, PhD

Memorial Sloan–Kettering Cancer Center
From Diagnostics to Theranostics: Expanding Horizons for Clinical Scientists in Imaging
10:00 a.m. – 11:00 a.m. Panel - Post-Graduate Opportunities
Panelists: Holly J. Humphrey, MD, MACP; William N. Kelley, MD
Moderator: David M. Markovitz, MD
10:00 a.m. – 11:00 a.m. Panel - Social Sciences and Humanities
Panelists: David Chan, MD, PhD; Joel Howell MD, PhD; Bapu Jena, MD, PhD
11:00 a.m. – Noon Panel - Policy
Panelists: Martin Burke, DO; Larissa Lapteva, MD, MHS; Lex Van Der Ploeg, PhD
Moderator: Jennifer M. Kwan, MD, PhD
11:00 a.m. – Noon Panel - MSTP Admissions Panel for Undergraduates
Panelists: Hossein Ardehali, MD, PhD; Lawrence (Skip) Brass, MD, PhD; Marcus Clark, MD; Anisley Valenciaga
Noon – 2:00 p.m. Residency Luncheon